01 - Preheat oven to 325°F (160°C). Line a baking sheet with parchment paper.
02 - If using fresh pumpkin seeds, rinse thoroughly to remove pulp, then pat dry with a clean kitchen towel.
03 - In a large bowl, mix pumpkin seeds with olive oil, smoked paprika, garlic powder, sea salt, black pepper, and cayenne pepper if desired, tossing until evenly coated.
04 - Spread the seasoned seeds in a single layer on the prepared baking sheet.
05 - Roast seeds for 20 to 25 minutes, stirring once halfway through cooking, until golden and crisp.
06 - Allow seeds to cool completely on the baking sheet before serving or transferring to an airtight container.